What are the symptoms of adrenal disease?
The adrenal gland is an important endocrine organ in the human body, located above the kidneys. It is mainly responsible for secreting a variety of hormones, such as adrenaline, cortisol, and aldosterone. When the adrenal glands function abnormally, it may cause a series of symptoms that affect your health. This article will detail the common symptoms of adrenal disease and attach structured data for readers to quickly understand.
1. Common symptoms of adrenal disease

Symptoms of adrenal disease vary depending on the specific type of disease. Here are some typical symptoms of several common adrenal diseases:
| disease type | Main symptoms |
|---|---|
| Cushing's syndrome | Weight gain (especially in the abdomen and face), thin skin that bruises easily, high blood pressure, elevated blood sugar, and muscle weakness |
| Adrenocortical insufficiency (Addison's disease) | Fatigue, weight loss, skin pigmentation, hypotension, loss of appetite, nausea and vomiting |
| Pheochromocytoma | Paroxysmal hypertension, headache, palpitations, excessive sweating, anxiety |
| primary aldosteronism | High blood pressure, hypokalemia, muscle weakness, polyuria, and thirst |
2. Analysis of specific symptoms of adrenal disease
1.Cushing's syndrome: Due to excessive secretion of cortisol, patients will have the typical "moon face" and "buffalo back", accompanied by fragile skin and mood swings.
2.Addison's disease: This is a disease of adrenal insufficiency. Patients often present with extreme fatigue and low blood pressure. In severe cases, adrenal crisis may occur.
3.Pheochromocytoma: This tumor causes excessive secretion of epinephrine and norepinephrine, triggering sudden high blood pressure and heart palpitations that usually last from minutes to hours.
4.primary aldosteronism: Excessive secretion of aldosterone can lead to sodium retention and potassium loss, leading to symptoms of hypertension and hypokalemia.
3. Diagnosis and treatment of adrenal disease
The diagnosis of adrenal disease usually requires a combination of clinical symptoms and laboratory tests. The following are common test methods:
| Check items | purpose |
|---|---|
| blood hormone testing | Measure hormone levels such as cortisol, aldosterone, and epinephrine |
| Urine hormone testing | Assess 24-hour hormone secretion |
| Imaging examination (CT/MRI) | Testing for tumors or growths in the adrenal glands |
| Functional test | Such as the dexamethasone suppression test, used to diagnose Cushing's syndrome |
In terms of treatment, depending on the type of disease, the following methods may be used:
-drug treatment: Such as hormone replacement therapy (for Addison's disease) or drugs that suppress hormone secretion (for Cushing's syndrome).
-surgical treatment: For adrenal tumors (such as pheochromocytoma), surgical removal is usually required.
-lifestyle adjustments: such as controlling salt intake (primary aldosteronism) or managing stress (Cushing's syndrome).
4. Prevention and precautions for adrenal disease
While some adrenal diseases cannot be completely prevented, the following steps can help reduce your risk:
1. Regular physical examination, especially for people with family history.
2. Avoid long-term use of high-dose corticosteroids unless specifically directed by your doctor.
3. Maintain a healthy lifestyle, including a balanced diet and moderate exercise.
4. Seek medical attention promptly when suspected symptoms appear to avoid delaying treatment.
5. For confirmed patients, medication must be strictly followed as prescribed by the doctor, and the dosage must not be adjusted at will.
5. Summary
Symptoms of adrenal disease range from high blood pressure to fatigue and weight changes, and can all be related to abnormal adrenal function. It is crucial to recognize these symptoms early and seek medical advice early. With proper diagnosis and treatment, most adrenal diseases can be effectively controlled. If you experience any of the above symptoms, it is recommended to consult an endocrinologist promptly.
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